Not a city, but Arkansas (Ar-can-saw) always confused me.
From the Mexican, Los Angeles should be 'los an-jhel-es'... (The Angels), but Los An-gee-lees is my personal pronunciation.
Of course, most spellings have been skewed by the horrificness that is American-English. I just refer to it as 'American' as I don't want to put my language to its name
