2D cockpit for takeoff and landing; other views once I'm on course. Since I tend to fly passenger jets pretty much exclusively, I need to see the artificial horizon, air speed gauge, flap location etc. etc. I only relax into other views once the autopilot is on.
Once you've taken off or landed, you can re-run in VC mode to see how it looks, but I wouldn't do it in real time! Too many passengers at risk!
(Mutter, mutter .. this is only a sim ... this is only a sim ...)
