There are very few aircraft in real life that can go all the way to the runway on autopilot alone, and that is usually reserved for extremely poor-visibilty approaches...
The only model I know of for MSFS that can do it is Maltby's stunning VC10, available right here at the V. There may be others... I don't know.
It autolands quite nicely, but the autopilot is not what you might be used to: very old and very English.

But I am not much of a jet jockey and I did fine with it, so anybody can.
In the end, though, I agree with Esselbach- other than the novelty of doing it once, what's the fun in letting the computer do all the flying?