Do you know how to use VORs in, say, a Cessna 172? The process of using them is much simpler in a 737 than in a 172. If you don't know how to use them in either, we'd be happy to give you a tutorial.
Also, most modern-day airliners don't navigate using VORs-VORs are only used as checkpoints and ways to confirm their position. Their system of navigation is through "High Altitude Airways", of which VORs are often waypoints. GPS is, in fact, the primary form of navigation. But they don't use direct GPS routing.
In the FS flight planner screen, when you select the departure and destination airports, right below si should say "VFR/IFR". Select IFR. Below that, it should say "Direct GPS/HAAWs/LAAWs/VOR to VOR". Select HAAWs (high altitude airways). Then hit "find route", and there you go. Normally, the waypoints will require a bit of editing-it usually has the first waypoint as the VOR of the departure airport.
Also, any waypoint within about 70 nm of your destination should be deleted, since you'll be manuevering on approach by then.
Well, I didn't answer your VOR question, but now you know how to flightplan at least
