Looks to me that they work from the old joystick or Media port found on older PC's. I think they will be driver dependent and that is if you have a joystick post on the mother board or sound card.
I'm just seeing them as a good starting point for the core mechanical work to which you can then completly alter/replace the interface circuitry. Those LOOK like metal units.....and well built. Beat the crap out of CH or Saitek plastic crap.