Second HDD Woes and Uninstall

So I have a good feeling my F: drive which is a 150Gb Raptor is dead. It has been around and working hard for around 3 years now.
The problem is I have programs installed on the F: drive and not the C:. How can I uninstall them from C:? The uninstaller for the programs is such as Empire/Napoleon Total War, Steam, Paint.NET is located on the corrupt drive.
I assume it will only be a matter of clearing and cleaning registry entries and any other files on C:. How will I accomplish that task without destroying my current fine computer.
Thanks
The problem is I have programs installed on the F: drive and not the C:. How can I uninstall them from C:? The uninstaller for the programs is such as Empire/Napoleon Total War, Steam, Paint.NET is located on the corrupt drive.
I assume it will only be a matter of clearing and cleaning registry entries and any other files on C:. How will I accomplish that task without destroying my current fine computer.
Thanks