I'm still a FS98 fan. It runs on anything. I recently bought a copy of Abacus' Co-Pilot on eBAY. It is supposed to automatically fly your plane from point-a to point-b, OR use your flightplan. It includes a scrolling map for ease of navigation.
It is complex to use, and compared with share-ware, such as EASYFLY by Warren software (1999), it pales. The only problem with EasyFly, is that they have a trial version on Flightsim.com that is limited in scope. If anyone has the full version, I sure would appreciate it.