Looking for a song, hopefully someone knows it

First I will say I have searched Google to no avail. I had a song on a burned CD that got ruined that I really enjoyed back in 2006. It was a duet rock or alternative song. The singers sounded like James Hetfield and Madonna. I have no idea what the title was and I have no idea what the lyrics were, but the lyrics I do remember was the woman singing either "There's a fire in your eyes" or heart, can't remember which. Then she sang "It's in your heart" and repeated it a few times. The beginning had him singing first, then her. It was on a burned CD containing Nightwish. However, I have every single Album of theirs and it's not them. I REALLY hope someone knows the song I am looking for as I have been looking for years. Kind regards, Jeremy 
