Take 1:
During a patient's two week follow-up appointment with his cardiologist, he informed me, his doctor, that he was having trouble with one of his medications.
Which one?" I asked.
"The patch. The nurse told me to put on a new one every six hours and now I'm running out of places to put it!"
I had him quickly undress and discovered what I hoped I wouldn't see: yes, the man had over fifty patches on his body!

Now the instructions include 'remove old patch before applying a new one'.
Dr. Rebecca St. Clair, Norfolk, VA