The key skill difference for flying twins, is mastering single engine (engine out) flight... the basics are the same... aside from the higher performance to get used to.
If your primary instructor was the guy who preached, "pitch for Vyse" after rotation (instead of Vy), he's laying the multi-engine foundation. Just like tapping the brakes and saying out loud "gear up", even when flying a fixed gear airplane, you get that stuff drilled into your reflexes.
( Vyse is the climb speed for a twin when an engine fails on takeoff )
Also, from a pilot's perspective, the only real concern about turbo-charging, is knowing the different MP/RPM relationships (the default Mooney is turbo-charged).. or if it's just turbo-normalization (turbo for maintaing sea-level MP to higher altitudes, not turbo for more HP), knowing how to manage that.
The TwinStar is an ideal, ME trainer.. 8-)

