Having planned my course in FS Navigator, I make a note of all the VOR and NDB frequencies en route on paper.
Tune my Nav1 radio to each one in turn, and set my course from the Compass reading on the VOR 1 Indicator, and then apply it to the Heading Indicator, and then set the Autopilot, with slight variations of the Heading Indicator Bug to keep on course.
The same with the ADF Indicator when tuned to the NDB Beacon.
It mostly gets me to my destination, safely!...

...!
(I also track myself on the GPS display).
Paul...G-BPLF...FS 2004...FS Nav... 8-)...!