A question about missions and planes

So, I was wondering, can you switch aircraft during a mission?
In example,
If you had to get from one place to another, could you go, say, from a lear, then, switch to a F16 add-on? would that effect the mission out-come?
Thanks.
~Airshow
In example,
If you had to get from one place to another, could you go, say, from a lear, then, switch to a F16 add-on? would that effect the mission out-come?
Thanks.

~Airshow